Abstract: A control method based on generalized predictive control(GPC) was proposed for a multivariable coupling system,Error weights could be self-regulated in order to reduce interactions in the system and improve dynamic performances of coupling loops.Compared with the conventional multivariable generalized predictive,the proposed method is characteristic of simplicity and small computational burden.The algorithm was applied to an auto-shape control and auto-gauge control system(ASC-AGC),and simulation results demonstrate its efficiency and correctness.